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Engage with us
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Search

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CVIM
openFMD
Contact us

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Our Scientists
Dr Joseph Newman

Postdoctoral Scientist

Dr Joseph Newman

Group

Viral Glycoproteins

Dr Joseph Newman

Group

Viral Glycoproteins

Publications

Shimmon G, Kotecha A, Ren J, Asfor A S, Newman J, Berryman S, Cottam E M, Gold S, Tuthill T J, King D P, Brocchi E, King A M Q, Owens R, Fry E E, Stuart D I, Burman A, Jackson T (2018)

Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays

Journal PLoS ONE

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Kristensen T, Newman J, Guan S H, Tuthill T J, Belsham G J (2018)

Cleavages at the three junctions within the foot-and-mouth disease virus capsid precursor (P1-2A) by the 3C protease are mutually independent

Journal Virology

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Mousnier A, Bell A S, Swieboda D P, Morales-Sanfrutos J, Pérez-Dorado I, Brannigan J A, Newman J, Ritzefeld M, Hutton J A, Guedán A, Asfor A S, Robinson S W, Hopkins-Navratilova I, Wilkinson A J, Johnston S L, Leatherbarrow R J, Tuthill T J, Solari R, Tate E W (2018)

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus

Journal Nature Chemistry

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Newman J, Asfor A S, Berryman S, Jackson T, Curry S, Tuthill T J (2017)

The cellular chaperone heat shock protein 90 is required for foot-and-mouth disease virus capsid precursor processing and assembly of capsid pentamers

Journal Journal of Virology

Read abstract

Logan G, Newman J, Wright C F, Lasecka-Dykes L, Haydon D T, Cottam E M, Tuthill T J (2017)

Deep sequencing of foot-and-mouth disease virus reveals RNA sequences involved in genome packaging

Journal Journal of Virology

Read abstract

Pagination

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Articles

Pink piglet standing on gravel

Pirbright scientists investigate pig coronavirus infection to understand COVID-19 in humans

Researchers at Pirbright have developed a pig respiratory coronavirus (PRCV) model which will help to understand how coronaviruses cause disease and how the immune system responds to them. Human coronaviruses such as Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS…

Coloured image of SARS-CoV-2 viruses

SARS-CoV-2 variants can infect a wider range of animal cells according to new research led by Pirbright

SARS-CoV-2, the virus that causes COVID-19, can potentially infect a wider number of animal species including rodents and ferrets, reveal Pirbright scientists. The study found that SARS-CoV-2 variants Alpha, Beta and Delta can infect more species compared to the ancestral virus strain, this is due…

A pig in hay with straw over face

22 January 2021

Early animal studies by Pirbright and Oxford yield promising results for new potential COVID-19 vaccine

Studies carried out by The Pirbright Institute and the University of Oxford have shown that Oxford’s new potential vaccine against COVID-19, named RBD-SpyVLP, produces a strong antibody response in mice and pigs, providing vital information for the further development of the vaccine. Although this…

Pigs in hay looking up at the camera.

Studies at Pirbright demonstrate two doses of Oxford University’s COVID-19 vaccine boosts immune response in pigs

The Pirbright Institute, working in collaboration with the University of Oxford, have successfully shown that two doses of the ChAdOx1 nCoV-19 (AZD1222) vaccine produce a greater antibody response than a single dose in pigs. The emergence and subsequent spread of SARS-CoV-2 has caused a global…

white mouse in tube with red eyes

26 September 2018

Engineering ‘Fab’ new ways of reducing animal use in foot-and-mouth disease diagnostics

A novel foot-and-mouth disease (FMD) diagnostic reagent has been developed by scientists at The Pirbright Institute. This has the potential to be used in FMD diagnostic tests, and will be significantly quicker to produce when compared to existing test reagents due to a simplified production…

cold virus

Breakthrough could make the common cold not so common

Researchers at The Pirbright Institute have helped in the development of a new molecule to treat a range of viruses including the common cold. In addition to the days of work lost due to illness, the common cold can cause complications in respiratory illnesses such as asthma and cystic fibrosis. The…

Foot-and-mouth disease virus capsid structure

12 December 2017

Protein shown vital for foot-and-mouth disease virus replication

Researchers at The Pirbright Institute have shown that when drugs are used to inhibit the cellular protein, hsp90, foot-and-mouth disease virus (FMDV) production is reduced. Hsp90 is a protein used by cells to fold other proteins correctly and it was shown to be required by FMDV to form the outer…

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