Our Group
The B Cell Dynamics group investigates how antiviral antibody responses develop, diversify and persist in livestock species.
We focus on the molecular, cellular and clonal mechanisms that determine whether B cell responses are protective, cross-reactive and durable.
Our work integrates high-resolution B cell phenotyping, antibody repertoire sequencing and their dynamics over time to understand how host responses shape disease outcome and vaccine efficacy.
Our Aims
- To understand how B cell responses are initiated, shaped and maintained.
- To identify the features of antibody responses that correlate with protection.
- To compare humoral immunity across livestock species.
- To inform the design of improved vaccines and diagnostics.
Our Research
Our research focuses on the development and function of antiviral antibody responses in cattle, pigs and poultry.
We investigate how B cell responses are shaped over time, how cross-protective antibodies emerge, and how these responses differ between species. We integrate cellular immunology and antibody repertoire analysis to uncover principles that can be translated into better disease control strategies.
Our Impact
Understanding how the immune system develops and responds to infection or vaccination in young animals will guide the design of more effective vaccines, providing earlier, broader and longer-lasting protection against viral diseases of livestock.
