Progress and knowledge gaps in Culicoides genetics, genomics and population modelling: 2003 to 2014
In the 10 years, since the last international meeting on Bluetongue virus (BTV) and related Orbiviruses in Sicily, there have been huge advances in explorations of the genetics and genomics of Culicoides, culminating in the imminent release of the rst full genome de novo assembly for the genus. In parallel, mathematical models used to predict Culicoides adult distribution, seasonality, and dispersal have also increased in sophistication, re ecting advances in available computational power and expertise. While these advances have focused upon the outbreaks of BTV in Europe, there is an opportunity to extend these techniques to other regions as part of global studies of the genus. This review takes a selective approach to examining the past decade of research in these areas and provides a personal viewpoint of future directions of research that may prove productive.