Postdoctoral Scientist

The Pirbright institute delivers world-leading research to understand, predict, detect and respond to viral disease outbreaks. We study viruses of livestock that are endemic and exotic to the UK, including zoonotic viruses, by using the most advanced tools and technologies to understand host-pathogen interactions in animals and arthropod vectors. Our major strength in understanding the immune systems of livestock provides a platform to control current diseases and respond to emerging threats. This important research would not be possible without the proportionate use of animals, which are integral to the development of new disease control measures such as vaccines and diagnostics. We have an establishment-wide commitment to the 3rs (replacement, reduction and refinement), high standards of animal welfare, a culture of care and openness.

Our institute is made up of a dynamic and vibrant community of staff covering a diverse set of chosen fields, backgrounds and experience. We all play a crucial role in furthering the institute’s aspirations, advancing the frontiers of science and knowledge through our excellent scientific research, knowledge sharing and contribution; with a real focus in improving the world in which we live. Our outlook is always balanced by our strong sense of purpose, values and behaviours and an unwavering commitment to a ‘one institute’ approach.

Organisation position and purpose

The T-cell Biology group investigates immune responses following infection and immunisation in various livestock species, with a primary focus on pigs. The analyses cover both lymphoid and non-lymphoid tissues and employ state-of-the-art technologies, including high-dimensional flow cytometry, single-cell RNA sequencing, and spatial transcriptomics. The group studies cells of both the innate and adaptive immune systems.

The postdoctoral scientist will contribute to the group’s research activities within Pirbright’s Institute Strategic Science Programme. The role includes supervisory responsibilities for students and offers the opportunity to develop an independent research portfolio. The job holder will report directly to, and work closely with, Group Leader Dr Wilhelm Gerner. There will also be strong collaboration with other scientists involved in the Institute Strategic Science Programme.

Main duties and responsibility 

Responsible for supporting the Institute’s Strategic Science Programme (ISSP), which will include:

• Conduct research contributing to the T-cell Biology group’s work within the Institute Strategic Science Programme (ISSP)
• Contribute to the supervision of students within the group
• Draft and write scientific reports and manuscripts
• Participate in sample collection during post-mortems of livestock
• Present research findings in internal meetings and at national and international conferences
• Assist with laboratory management, including ordering supplies, maintaining equipment, and managing sample inventories
• Serve on committees, steering groups, and other relevant meetings as appropriate
• Ensure that all laboratory work is conducted safely and in accordance with local health and safety policies
• Develop and maintain documentation related to health, safety, and biosecurity to support a safe working environment
• Engage in outreach activities as appropriate

This job description is only an outline of the tasks, responsibilities and outcomes required of the role. The jobholder will carry out any other duties as may be reasonably required by his/her line manager. The job description and personal specification may be reviewed on an ongoing basis in accordance with the changing needs of The Pirbright Institute.

Specific requirements

Essential 

• A PhD in a relevant branch of the biosciences
• Strong knowledge of basic immunology and immunological concepts
• Documented experience in multi-colour flow cytometry
• Documented experience in immunofluorescence imaging
• Evidence of excellent oral and written communication skills

Desirable

• Experience with basic molecular biology techniques
• Experience in performing single cell RNA-sequencing experiments
• Experience in performing spatial transcriptomics experiments
• Experience in conducting animal experiments with livestock
• Evidence of networking skills with the ability to build effective collaborative relationships 

Due to the nature of the work carried out by Pirbright, all successful applicants will be required to go through a comprehensive screening process including reference and qualification checks, financial and security clearances.

What we offer

• Generous Group Personal Pension Scheme and life cover (subject to age and earnings)
• 25 days annual leave per annum, pro rata, plus 10.5 public and privilege days
• Buy and sell annual leave
• Option to carry over up to two weeks annual leave
• Pirbright gym with subsidised membership
• Pirbright social club
• Pirbright Lifestyle Hub (employee discount site)
• Cycle to work
• Subsidised staff restaurant
• Childcare allowance
• Free onsite parking
• Electric Car charging facilities 

Due to the high volume of applications we receive, if you have not heard from us within one month from closing date of the vacancy, then please contact us on jobs@pirbright.ac.uk for an update.